Spheroid Culture System: Advantages, and Mechanism
Spheroid culture system is a revolutionary 3D cell culture system that is relatively low tech, easy to use and easily reproducible. Spheroid system aids the formation of in-vivo like cell structure, where cells maintain their native phenotype, and extra-cellular matrix
Different approaches for 3D primary cell culture model development
Primary cell cultures are ex-vivo cultures produced from cells that are freshly harvested from a multicellular organism. Generally, primary cell cultures are more representative of in-vivo tissues than immortalized cell lines (1). However culturing primary cells are not without its
Spheroids Vs. Organoids, How do you choose?
The terms spheroids and organoids are often used interchangeably. They are similar in many ways but also different in what they are made up of, and what they do. Depending on the type of data required from 3D culture, it
Perfect 3D spheroids for cancer research with BIOFLOAT
Cancer research relies on cell based model systems to understand the growth and progression of tumors, and subsequently the discovery of new therapeutic drugs. Traditional monolayer cultures have been widely used in this regard due to its ability to generate
Optimising you experiments with BioFloat plates
Biofloat coated plates are easy to use, versatile and reliable. There is no specific protocol for using the plates, however, for maximum reliability and reproducibility of experiments, please follow the following guidelines. 1. Seeding density- The seeding density is dependent on
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3D dog liver spheroids for in vitro preclinical testing
We happy to share our latest article in the journal Biospektrum 07/21 showing the fast and reliable generation of dog liver spheroids in BIOFLOAT plates. Big thanks to our Co-Authors Barbara Birk and Carina Oberfrank from BASF SE, Germany and
Amphiphilic Copolymers for Versatile, Facile, and In Situ Tunable Surface Biofunctionalization
[vc_row][vc_column][vc_column_text] We are proud to present this new paper on “Amphiphilic Copolymers for Versatile, Facile, and In Situ Tunable Surface Biofunctionalization” which was just published together with our long-standing collaborators at the Leibniz Institute of Polymer Research Dresden (IPF). [/vc_column_text][vc_empty_space][mkdf_button text="Download" target="_blank"
The next generation of low adhesion
INTRODUCTION Cell based in vitro assays are becoming more important in the basic research but also in applied research in pharmacology and toxicology. All these methods are generating important information and finally help to understand the human (patho-) physiology. In order
The Dimension Counts : Uniform 3D cell speheroids
A new technology enables the production of uniform 3D cell spheroids for stem cell and cancer research and preclinical drug development. In order to understand the cause of many diseases in humans, suitable model systems are needed that enable scientists in