3D spheroid culture in environmental toxicology
Spheroid culture has found applications in the field of environmental toxicology as a valuable tool for assessing the effects of environmental contaminants, pollutants, and chemicals on biological systems. The spheroid cell culture approach provides several advantages for toxicological studies related to
Factors affecting tumor spheroid formation for cancer research
Tumor spheroids are three-dimensional cell culture models that have gained significant attention in cancer research because they provide a more physiologically relevant environment for studying tumor biology compared to traditional two-dimensional cell culture systems. 3D spheroids contain a dense network of
Spotlight on the applications of precision medicine
Modern medicine and therapies are designed to treat large groups of people with the same disease. Doctors may consider the sex, age, or medical history of the patient but most of the treatments are still based on what is most
The Shared Characteristics Of Spheroids And Tumors
Since its introduction, 3D cell culture has revolutionized cancer research by providing an efficient and modifiable research platform, that recapitulates in vivo like cell structure, function, gene expression and tissue microenvironment, all of which are important parameters for the drug
A comparison of 2D and 3D cell cultures
Cell culture is the process of growing cells outside of their natural environment, typically in a laboratory setting. It involves the cultivation of cells in a controlled environment, usually in a special liquid medium that provides the necessary nutrients and
The most common primary cells used in research
Human primary cells are isolated directly from human tissues and maintain the physiological characteristics of their original tissue. This article discusses the most common primary cells used by scientists (1,2). Endothelial cells In the human body, endothelial cells form a single-cell thick-walled
What are primary cells : advantages and limitations
Primary cell cultures refer to the cultivation of cells that are directly isolated from human or animal tissues and processed to grow under controlled conditions in vitro. They represent the in vivo state of cells more closely than immortalized cell
Introduction to cell culture and its applications
Cell culture is one of the crucial tools in basic scientific research. Cell culture refers to the cultivation in a controlled environment of cells derived from an animal or a plant. Today, various cell culture techniques are used in laboratories
How to choose the right cell line for your experiments
Cell lines are an easy and inexpensive tool used by researchers routinely. With the plethora of cell lines available today, selecting the right cell line for your project is fundamental for getting reliable results. Cell line contamination, misidentification, source, genetics,
Evolution Of 3D Cell Culture
In the past decade research has experienced drastic changes in the development of an alternative research method over the traditional use of animal models as an investigative platform. 2D Monolayer in vitro cultures are effective as drug screening platform but