Cell culture is an important and necessary tool in drug discovery, cancer research as well as in stem cell studies. Cells are cultured using two-dimensional methods, but new and improved methods have now evolved and…
Among the neurodegenerative diseases, Multi sclerosis is the most common chronic disease prevalent among the young adult population with an early onset at 20-40 years of age, with a high occurrence among women (1). MS…
In the past decade 3D liver cultures as developed in leaps and bounds for study of liver functions, and disease progression. Most of these culture systems are also adopted commercially, for testing drug toxicity, drug…
Among the neurodegenerative diseases, MS is the most common chronic disease prevalent among the young adult population with an early onset at 20-40 years of age, with a high occurrence among women (1). MS is…
The limitations of 2D cultures have paved the way for the development of 3D cell culture models of Alzheimer’s disease (AD). AD is a neurodegenerative disorder comprised of progressive decline of cognitive abilities and behaviour…
Wondering what these tiny clumps of cells are? let’s have a look. WHAT ARE SPHEROIDS? Spheroids are three-dimensional (3D) cell aggregate to better stimulate a in-vivo like environment as compared to a two-dimensional model. Compared…
In the recent years most drugs designed to treat neurodegenerative disorders, have failed to produce desired effects at the clinical trial phase. This points towards a strong inability in conventional 2D culture assays, and animal…
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) pandemic has been at the center of attention in public health due to its severity resulting in high mortality rates around the globe. 2D and 3D cell…
Respiratory Syncytial Virus (RSV) is one of the most common respiratory tract viruses with high mortality rate among infants below the age of 5. Within the adult population it can cause chronic disease and weaker…
3D cultures are now being extensively used to study the effects of respiratory viruses on host tissues. 3D cultures contain a modifiable platform to culture cells, that allows for development of in-vivo like structure and…