3D bioprinting or bioprinting is an additive manufacturing process that uses organic and biological materials such as living cells and nutrients as bioinks to combine and create artificial structures that imitate natural human tissues. Charles Hull was the first one…
Cell culture is an indispensable tool for the investigation of basic scientific research questions. To grow and maintain cells, cell culture media and supplements critical for their support are very important. Essential cell culture media components include carbohydrates, amino acids,…
Modern drug discovery processes have encountered major setbacks over the past decades, despite technological advances in analytical tools and the development of research model. This is primarily due to the lack of predictive models that reliably mimic the complex structure…
In the recent decades, 3D bioprinting methods have been widely used in tissue engineering and regenerative medicine. Additionally, these techniques have also emerged as a novel approach in the development of in vivo-like 3D cell culture models (1-3). Advantages of…
Cell culture or tissue culture is one of the techniques that are mostly used in life sciences in which cells are grown under controlled conditions, outside their natural environment. The cells or tissues, are removed from their original sources and…
Growth media remains a key component of 3D cell culture experiments ensuring cells can thrive outside their natural environment. The continuous development and optimization of cell culture media provide new insights into the association between cells and cell culture media…
Since the early 1900s, the two-dimensional (2D) cell culture method is used to culture cells and grow them in favorable artificial conditions (1) thereby playing a vital role in biomedical research (2). In line with the limitations of 2D cell…
Cell-based assays are one of the important pillars of the drug discovery process to provide a simple, fast, and cost-effective tool to avoid cost-intensive animal testing. To date, the traditional two-dimensional (2D) cell monolayers are the preferred method to culture…
Three-dimensional (3D) cell culture technology has become one of the main focuses of tumor cell biology, using its various methods and materials to mimic the in vivo microenvironment of tumor cells cultured ex vivo. 3D culture techniques promise to be…
Two-dimensional (2D) cell cultures have been used by researchers since the early 1900s, but we are well aware of how growing cells on planar surfaces has some drawbacks. Cells grown in vitro in 2D space don’t behave like cells found…