Space exploration has always captured the human imagination, and as we venture beyond our planet, the study of human physiology in microgravity environments has become increasingly vital. 3D organoids, miniature organ models grown from human…
Despite the significant advances in using animal models in medical research, some preclinical studies from those models failed to be translated into clinical practice successfully. This could be due to subtle differences in the brain…
Cancer is one of the most threatening diseases and leading cause of death worldwide (1). Intra- and intertumoral heterogeneity is often responsible for metastasis formation, treatment failure, and therapy resistance. The increase in the cost…
Regenerative medicine refers to the method of replacing, engineering or regenerating human or animal cells, tissues, or organs with the aim to restore normal physiological functions (1). It has the potential to engineer damaged tissues…
Three-dimensional (3D) organoid technology has become popular among researchers in the past decade because of its ability to recapitulate the physiology and genetics of organs or tissue samples. Despite the promising applications of organoids in…
Organoids are miniaturized tissue cultures that are derived from stem cells or tissue-specific progenitor cells. Organoids have made it possible to create individual, complex, and self-organizing 3D tissue cultures bearing a resemblance to a patient’s…
Organoids are in vitro miniaturized three-dimensional (3D) model systems of organs that gained huge interest in the last decade. Organoids are self-organizing culture systems generated from stem cells or tissue-specific progenitor cells. Stem cells divide…
Organoid models are a popular and reliable method in 3D cell culture. Organoids are 3D cellular structures, derived from either stem cells or organ specific progenitor cells. When provided with an external scaffold like Matrigel,…
In the recent decades, 3D bioprinting methods have been widely used in tissue engineering and regenerative medicine. Additionally, these techniques have also emerged as a novel approach in the development of in vivo-like 3D cell…
Using organoids to study immunotherapy has been an emerging technique. In a study published in 2019, a method of co-culturing tumour organoids with peripheral blood lymphocytes generated immune cells that recognize and kill autologous tumour…