High throughput screening
High throughput screening (HTS) is a technique utilised in scientific experimentation in fields of biology, materials science and chemistry. It has become the method of choice in drug discovery processes. HTS utilises advanced robotics, data processing software, liquid handling devices
Scaffold free 3D cell culture models for high throughput screening
Scaffold free 3D cultures are cultivated in specialised cell repellant culture plates that causes cells to self aggregate. These involve hanging drop microplates, low adhesion plates with specialised polymer coating such as BIOFLOAT 96-well plates that encourages spheroid formation, or
Scaffold dependent 3D models for high throughput screening
Scaffold dependent 3D cell cultures rely on physical support that ranges from mechanical surfaces to extra cellular matrix (ECM) like structures on which cells are cultivated to aggregate, divide and migrate. The physical and chemical properties of the scaffold will