Stem cells are unspecialized cells of the human body with the ability to self-renew and differentiate into any type of cells of an organism. Recently, there has been an explosion of interest in stem cells within the scientific and medical…
Stem cell banking is the process of isolating stem cells from the body of a donor, processing them, and storing them for potential future use in the context of stem cell research or regenerative medicine. The low temperature of stem…
Stem cells are undifferentiated cells that are present in the embryonic, fetal, and adult stages of life and are characterized by the ability to extensively proliferate and differentiate into different types of cells and tissues (1). The major characteristics of…
In the past decade research has experienced drastic changes in the development of an alternative research method over the traditional use of animal models as an investigative platform. 2D Monolayer in vitro cultures are effective as drug screening platform but…
Organoids are 3D complex cluster of cells, derived from either stem cells or organ specific progenitors. When these cells are provided with an external scaffold like Matrigel, they form a complex cluster of cells that later differentiate to from a…
Colorectal cancer remains the second highest cause of death among all cancer-related mortalities. This is primarily due to tumor metastases and the inefficiency of available chemotherapeutic treatments (1,2). OoC models of colorectal cancers have been developed, however they are less…
The immune system is a host defense system and comprises many biological elements ranging from white blood cells to entire organs and many complex biological processes. The function of the immune system is to protect the host from pathogens and…
The immune system has a vital role in defending the body from harmful substances, germs, and thus infections. It is made up of a complex network of cells, chemicals, tissues, and organs that recognize invaders and mount an immune response…
Traditional tissue engineering methods showed limited success in the fabrication of complex 3D shapes resulting in non-feasible clinical applications. Over the past decade, 3D bioprinting technology emerged as a powerful tool in the field of tissue engineering to fabricate personalized…
Three-dimensional (3D) bioprinting uses 3D printing–like techniques to combine cells, growth factors, and other biomaterials to fabricate biomedical structures to imitate natural tissue characteristics. 3D bioprinting uses a layer-by-layer method to deposit bioinks to create tissue-like structures that are later…