Introducing the New BIOFLOAT™ Cell culture surface

The BIOFLOAT™ cell culture plates are coated with a polymeric coating rendering the surface non-adhesive and highly cell repellant. This prevents cell adhesion to the culture plate and therefor allows the cultivated cells to “stick” to each other, forming cell-cell contacts.

Spheroids cultivated in BIOFLOAT™ coated surfaces are uniform and round in shape. Additionally, single spheroids can be formed in each well in relatively short period of time. Uniformly shaped spheroids increase the reproducibility of your results, and make it an excellent platform for high throughput analyses.

Ready-to-use for spheroid cell culture

The BIOFLOAT™ 96-well plate provides a highly defined, fully inert, and cell-repelling surface.

Product Characteristcs

Plate color: clear
Well bottom: round (U – bottom)
Well bottom color: clear
Well volume: 310 µl
Recommended working volume: 100 µl
Dimensions: 85.20 mm (width) x 16.55 mm (height) x 127.80 mm (length)
Array: 8×12
Material: Polystyrene (PS)
Temperature range: – 20 °C to + 50 °C
Sterile: yes
Quantity: bag of 4 plates with resealable snap lock

4 plates per pack 

RESEARCH USE ONLY. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.

Ordering more than 24 plates – FREE EXPRESS SHIPPING (WORLDWIDE)

Ready-to-use for spheroid cell culture

The BIOFLOAT™ 384-well plate provides a highly defined, fully inert, and cell-repelling surface.

Product Characteristcs

Plate color: clear
Well bottom: round (U – bottom)
Well bottom color: clear
Well volume: 90 µl
Recommended working volume: 50 µl
Dimensions: 85.48 mm (width) x 14,4 mm (height) x 127.67 mm (length)
Array: 16×24
Material: Polystyrene (PS)
Temperature range: – 20 °C to + 50 °C
Sterile: yes
Quantity: bag of 4 plates with resealable snap lock

4 plates per pack 

RESEARCH USE ONLY. NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE.

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BIOFLOAT FLEX™ is a convenient and flexible solution for your protein and cell culture assays. It works on a broad range of materials, including pastic and glass, without complicated coating procedure. One pipetting step is sufficient to obtain full surface passivation in the nanometer scale without alteration of the geometry of the substrate.

Moreover, the integrity of the inert surface is not influenced by cell culture media. Cell culture plates coated with BIOFLOAT™ FLEX are highly cell-repellent and rapidly induce the formation of highly uniform spheroids within just a few hours, saving you valuable time during your experiments.

Quick: BIOFLOAT™ FLEX coating rapidly adsorbs to the cell plate surface without the need for surface preparation.
Stable: BIOFLOAT™ FLEX coating is highly scratch-resistant and robust against media components.
Inert: BIOFLOAT™ FLEX coating avoids unspecific surface binding of proteins and cells.

– 250 ml per bottle –

Available for research use only

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Ready-to-use for spheroid cell culture

The BIOFLOAT™ 96-well plate provides a highly defined, fully inert, and cell-repelling surface.

Product Characteristcs

Plate color: clear
Well bottom: round (U – bottom)
Well volume: 310 µl
Dimensions: 85.20 mm (width) x 16.55 mm (height) x 127.80 mm (length)
Material: Polystyrene (PS)
Temperature range: – 20 °C to + 50 °C
Sterile: yes
Made in Germany

Quantity: bag of 4 plates with resealable snap lock

Want to make sure our BIOFLOAT™ lineup is suitable for your cell culture?

We are confident in the quality of our products and you can also be convinced of this.
We invite you to try our products to get  perfect spheroids and organoids for your application.

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The reliable quality of the BIOFLOAT™ cell culture surface enables the formation of perfect spheroids even for challenging cells. This also includes cells that do not form spheroids on existing products.

      Cardiac myocytes

      Endothelial cells

       Primary hepatocytes

       Alveolar epithelial cells

      Neuronal stem cells

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Cardiac myocytes

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Endothelial cells

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Primary hepatocytes

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Alveolar epithelial cells 

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 Neuronal stem cells

Fibroblasts (M. musculus)
Squamous cell cancer cell line (H. sapiens)
Melanoma cell line (M. musculus)
Colon carcinoma cell line (H. sapiens, Caucasian)
Pancreatic adenoma cancer cell line (H. sapiens)
Ovarian cell line (C. griseus)
Epithelial breast cancer cell line (stem cell-like)
(H. sapiens)
Tumourigenic breast epithelial stem cell line from
D492 cells (H. sapiens)
Pancreatic cancer cell line (H. sapiens)
Embryonic stem cells (S. scrofa domesticus)
Pancreatic adenoma cancer cell line (H. sapiens)
Lung adenocarcinoma cell line (H. sapiens)
Breast cancer cell line (H. sapiens)
Colon cancer cell line (H. sapiens)
Primary dental pulp stem cells (H. sapiens)
Pancreatic cancer cell line (H. sapiens)
Immortalised osteoblasts (H. sapiens)
Venous endothelial cells (H. sapiens)
iPSC-derived hepatocytes
Breast cancer cell line (H. sapiens)
Pancreatic cell line (H. sapiens)
Hepatic stellate cells/Ito cells (F norwegicus)
Hepatic stellate cells/to calls (r. Sapiens)
B-lymphocyte cell line from myeloma patients
Immortalised astrocytes (H. sapiens)
Differentiated fatty cell organoids from pluripotent stem cells
Endometrial organoids from detached primary cells (non-human primates)
Fibroblast progenitor cells (M. cerebralis)
IPSC-derived cardiomyocytes (H. sapiens)
Liver organoids (differentiated) (M. musculus)
Neuronal stem cells (HN9 differentiated)
Primary hepatocytes (H. sapiens, M. musculus,
M. fascicularis, C. lupus famillaris)

Raw Material Processing

The product does not use any rawmaterials of animal
or biological origin and therefore does not have TSE/BSE.

The polymer raw materials used for coating plates were positively evaluated
for quality consistency using GPC, GC-MS and NMR spectroscopy.

The sterile, non-pyrogenic/endotoxin-free, non-cytotoxic, DNase-/RNase-/DNA-free multi-well plates were coated using pipetting robots.
Coated plates were sterilized by electron beam irradiation according to DIN EN ISO 11137

Want to create perfect uniform spheroids?

Rapid spheroid formation

Shorten your experiment timelines. Single spheroids form faster on BIOFLOATTM surfaces than on most other ultra-low attachment surfaces.

Round and Uniform

The 3D cell culture and maintenance on the BIOFLOAT™ surfaces result in highly uniform spheroids and perfect data consistency. Cell satellites and irregular aggregations are eliminated.

Reliable spheroid culture

The reliable quality of the BIOFLOAT™ surface makes it a premium product for spheroid and organoid culture, including cells which fail to generate spheroids on existing products.

The BIOFLOAT™ is trusted by leading Pharma and R&D Institutions

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Why use BIOFLOAT™ coating technology for your research?

BIOFLOAT™ coating technology provides a highly defined, fully inert cell- and protein-repellent surface for cell culture labware and devices. Compact and reproducible spheroids are rapidly generated on BIOFLOAT™ coated surfaces, even with challenging cell types. Sticky proteins are inhibited to adsorb to your cell culture labware.

Which cells are compatible with the BIOFLOAT™ coating technology?

BIOFLOAT™ coating technology is compatible with broad range of human and animal derived cell lines or primary cells. This new technology is developed to generate cell spheroids; therefore, any cell line can be used which are known to form such spheroids or you can develop new organoid models containing spheroids with cell lines of your choice. In Tab. 1 you can find a selected number of cell lines cultured with BIOFLOAT™ coating technology.

Tab. 1 List of cell lines

BIOFLOAT FLEX solution for 3D organoid cell culture and research

Which products are available with the BIOFLOAT™ coating technology?

Choose between the ready-to-use 96-well plate, 384-well plate or DIY BIOFLOAT™ FLEX coating solution to modify a broad range of plastic and glass surfaces.

Does the coating react with chemicals?

All BIOFLOAT™ products do not contain any reactive groups, which can react with other chemicals.

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You can request your quotation now!

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